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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38836L | Protease-Activated Receptor-1, PAR-1 Agonist acetate | Protease-activated Receptor | |
Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi... | |||
T38836 | Protease-Activated Receptor-1, PAR-1 Agonist | ||
Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio... | |||
T36288 | Protease-Activated Receptor-1, PAR-1 Agonist TFA | ||
Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac... | |||
T36289 | Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA | ||
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1]. | |||
TP1046 | SLIGRL-NH2 | Protease-Activated Receptor-2 Activating Peptide | Protease-activated Receptor |
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus. | |||
T36286 | Protease-Activated Receptor-3 (PAR-3) (1-6), human | ||
TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells. | |||
T1986L | Atopaxar Hydrobromide | Protease-activated Receptor | |
Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. | |||
T1986 | Atopaxar | E5555,ER-172594-00 | Protease-activated Receptor |
Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. | |||
T7137 | I-191 | Protease-activated Receptor | |
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. | |||
TQ0012 | AZ3451 | Protease-activated Receptor | |
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). | |||
TP1046L | PAR-2 Activating Peptide acetate | SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate | Protease-activated Receptor |
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2). | |||
TP1065 | PAR-4 Agonist Peptide, amide TFA | PAR-4-AP (TFA),AY-NH2 (TFA) | Protease-activated Receptor |
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b... | |||
T7623 | PAR-4 Agonist Peptide, amide | AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP | Protease-activated Receptor |
PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4). | |||
T7625 | TRAP-6 | PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA) | Protease-activated Receptor |
TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1). | |||
T1893 | Parmodulin 2 | ML 161 | Protease-activated Receptor |
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... | |||
T7513 | Protease-Activated Receptor-2, amide | SLIGKV-NH2 | Protease-activated Receptor |
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M) | |||
T2370 | AC-55541 | AOB2796 | Proteasome , Protease-activated Receptor |
AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. | |||
T8917 | PAR-2-IN-1 | IUN76750 | Protease-activated Receptor |
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects. | |||
T7013 | Vorapaxar | SCH 530348,MK-5348 | Protease-activated Receptor |
Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM). | |||
T12870 | SCH79797 dihydrochloride | Apoptosis , Others , Protease-activated Receptor | |
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects. |